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rhBPM-2 with allograft effective for reconstruction of diaphyseal tibial fractures
August 2013
rhBPM-2 with allograft effective for reconstruction of diaphyseal tibial fractures
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:2
Recombinant Human BMP-2 and Allograft Compared with Autogenous Bone Graft for Reconstruction of Diaphyseal Tibial Fractures with Cortical Defects
J Bone Joint Surg Am. 2006 Jul;88(7):1431-41.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
30 patients with a tibial diaphyseal fracture and a residual cortical defect were randomized to receive either an autogeneous bone graft or an allograft with recombinant human bone morphogenetic protein-2 (rhBMP-2) to reconstruct the tibial defect. Surgical morbidity, clinical and radiographic signs of healing, and impact on health related quality of life (Short Musculoskeletal Function Assessment...
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