Single-dose epidural DepoDur is a safe and effective analgesic after knee arthroplasty
Evaluation of a single-dose, extended-release epidural morphine formulation for pain after knee arthroplastyJ Bone Joint Surg Am. 2006 Feb;88(2):273-81
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168 patients were randomised to receive either a single-dose, extended-release epidural morphine formulation intervention (DepoDur) at 20 or 30 mg, or a sham epidural injection after undergoing elective unilateral knee arthroplasty. The primary outcomes were pain and safety. Results indicated that the DepoDur intervention provided a safe and efficacious method of analgesia for patients up to 48 ho...
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