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Acetaminophen is a suitable treatment for moderate osteoarthritis pain of the knee
May 2013
Acetaminophen is a suitable treatment for moderate osteoarthritis pain of the knee
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
A 4-week randomized study of acetaminophen extended-release vs rofecoxib in knee osteoarthritis
Osteoarthritis Cartilage. 2009 Jan;17(1):1-7. Epub 2008 Jul 21Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
403 patients suffering from moderate pain associated with osteoarthritis (OA) of the knee were randomized into three groups. The groups consisted of an acetaminophen extended-release (APAP ER) group, a 12.5 mg rofecoxib group, and a 25 mg rofecoxib group. Following four weeks of treatment each group produced a significant reduction in WOMAC pain scores from baseline measures. APAP ER was found to ...
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