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Prophylactic Doxazosin for Minimizing Postoperative Urinary Retention After Total Joint Arthroplasty

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Ace Report Cover
April 2023

Prophylactic Doxazosin for Minimizing Postoperative Urinary Retention After Total Joint Arthroplasty

Vol: 303| Issue: 4| Number:9| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Prophylactic doxazosin reduces urinary retention and promotes recovery after total joint arthroplasty: A randomized controlled trial.

Front Pharmacol . 2023 Jan 9;13:1016203.

Contributing Authors:
Z Ding J Cao C Huang K Zhou H Wang Z Zhou

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Synopsis

One hundred and seventy male patients undergoing total joint arthroplasty (hip or knee) were randomized to receive either doxazosin (n=85) or placebo (n=85). The primary outcome of interest was the incidence of postoperative urinary retention (POUR). Secondary outcomes included hospital length of stay, daily ambulation distance, pain on a Visual Analog Scale (VAS), opioid consumption, blood pressu...

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