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Intra-Articular Botulinum Toxin A for Knee Osteoarthritis
March 2023
Intra-Articular Botulinum Toxin A for Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy and Safety of Intra-Articular Botulinum Toxin A Injection for Knee Osteoarthritis: A Systematic Review, Meta-Analysis, and Meta-Regression of Clinical Trials.
JB JS Open Access. 2023 Jan 20;8(1):e22.00121.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Six randomized controlled trials containing a total of 446 patients with knee osteoarthritis were included in this systematic review and meta-analysis comparing intra-articular botulinum toxin A injections vs. control (placebo injection; education only). The pooled outcomes of interest were pain on a Visual Analog Scale (VAS) and the Western Ontario and McMaster Universities Osteoarthritis index (...
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