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Low-Dose vs. High-Dose Tranexamic Acid in Adult Spinal Deformity Surgery
December 2022
Low-Dose vs. High-Dose Tranexamic Acid in Adult Spinal Deformity Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Randomized, controlled trial of two tranexamic acid dosing protocols in adult spinal deformity surgery
Spine Deform. 2022 Nov;10(6):1399-1406.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Fifty-two adults undergoing multi-level fusion surgery for adult spinal deformity were randomized to receive a high-dose tranexamic acid regimen (n=25) or a low-dose tranexamic acid regimen (n=27) for the minimization of blood loss. Outcomes of interest included estimated blood loss, blood loss as a percentage of body volume, transfusion volume, and length of stay, and the incidence of complicatio...
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