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Effects of Tranexamic Acid and Dexamethasone on Inflammatory Responses, Pain, and Function After THA
December 2022
Effects of Tranexamic Acid and Dexamethasone on Inflammatory Responses, Pain, and Function After THA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Application of dexamethasone combined with tranexamic acid in perioperative period of total hip arthroplasty
Medicine (Baltimore) . 2022 Oct 21;101(42):e31223.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred patients undergoing total hip arthroplasty were randomized to receive tranexamic acid with dexamethasone (n=50) or tranexamic acid alone (n=50). Outcomes of interest were CRP and IL-6, pain scores, POVN incidence, and use of analgesics after 24, 48, and 72 hours. Significant differences were reported in CRP and IL-6 levels at all time points with lower levels in the TXA+DEXA group. Sig...
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