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Remimazolam Besylate vs Dexmedetomidine for Sedation in Non-Intubated Geriatric Patients
October 2022
Remimazolam Besylate vs Dexmedetomidine for Sedation in Non-Intubated Geriatric Patients
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy and Safety of Remimazolam Besylate versus Dexmedetomidine for Sedation in Non-Intubated Older Patients with Agitated Delirium After Orthopedic Surgery: A Randomized Controlled Trial
Drug Des Devel Ther. 2022 Aug 1;16:2439-2451. doi: 10.2147/DDDT.S373772. eCollection 2022.. 2022 01-Aug;():. 10.2147/DDDT.S373772Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighty geriatric patients with agitated delirium after orthopaedic surgery were randomized to receive remimazolam besylate (n=40) or dexmedetomidine (n=40) for the resolution of agitation. The primary outcome of interest was the time to resolution of agitation. Secondary outcomes of interest included sedation outcomes, length of stay, and adverse events, as well as vital signs and arterial blood g...
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