
Intraoperative Ketamine vs Placebo for Rebound Pain in Upper Limb Surgeries

Intraoperative Ketamine vs Placebo for Rebound Pain in Upper Limb Surgeries
Evaluation of intraoperative ketamine on the prevention of severe rebound pain upon cessation of peripheral nerve block: a prospective randomised, double-blind, placebo-controlled study.
Br J Anaesth . 2022 Apr;128(4):734-741.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred and nine patients undergoing upper limb surgery under an axillary plexus block were randomized to receive either intraoperative ketamine (n = 54) or placebo (n = 55; saline) for the prevention of severe rebound pain upon the cessation of a peripheral nerve block. All patients received an optimal preoperative multimodal analgesic treatment including intraoperative ketorolac and paraceta...
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