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Improved Knee Joint Structure but Limited Symptom Alleviation with Sprifermin Injections for Knee OA
June 2021
Improved Knee Joint Structure but Limited Symptom Alleviation with Sprifermin Injections for Knee OA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy and safety of sprifermin injection for knee osteoarthritis treatment: a meta-analysis
Arthritis Res Ther. 2021 Apr 9;23(1): 107.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eight randomized controlled trials containing a total of 2671 patients suffering from symptomatic knee osteoarthritis (OA) were included in this meta-analysis comparing injections of sprifermin to placebo. Pooled outcomes of interest include the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score and its subscores (i.e., pain, function, and stiffness), changes in car...
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