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ACE Report #128
Ace Report Cover Osteoarthritis

Glucosamine sulfate ineffective for chronic low back pain and degenerative lumbar OA


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Effect of glucosamine on pain-related disability in patients with chronic low back pain and degenerative lumbar osteoarthritis: a randomized controlled trial

JAMA. 2010 Jul 7;304(1):45-52.

Contributing Authors: P Wilkens IB Scheel O Grundnes C Hellum K Storheim

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Synopsis

250 patients (>25 yr) with chronic LBP(>6 month) and degenerative lumbar osteoarthritis(OA) were randomized to be administered 1500mg per day of glucosamine or placebo for 6 months duration. At 12 month time point, glucosamine sulfate was deemed ineffective in treating chronic LBP and other symptoms of degenerative lumbar osteoarthritis.

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