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Local TXA Reduces Blood Loss vs Intravenous TXA in Patients Undergoing Total Hip Replacement

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Ace Report Cover
December 2020

Local TXA Reduces Blood Loss vs Intravenous TXA in Patients Undergoing Total Hip Replacement

Vol: 9| Issue: 12| Number:4| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Better Treatment Values in Local Application of Tranexamic Acid (TXA) than Intravenous Application with the Same Dose in Total Hip Arthroplasty.

Adv Ther. 2020 Oct;37(10):4346-4355.

Contributing Authors:
X Zhang L Wen J Pan D Ma

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Synopsis

Seventy-two patients scheduled for a primary, unilateral total hip replacement were randomized to receive a local administration of tranexamic acid (TXA) or intravenous administration of TXA at the same dosage. Outcomes of interest included the following: total blood loss, hidden blood loss, incidence of blood transfusion, hematocrit (Hct) and hemoglobin (Hb) levels, C-reactive protein (CRP) and i...

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