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Similar Blood Loss and Peri-Operative Outcomes with IV and Oral TXA for TKA/THA Patients
November 2020
Similar Blood Loss and Peri-Operative Outcomes with IV and Oral TXA for TKA/THA Patients
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparison of oral versus intravenous tranexamic acid in total knee and hip arthroplasty: A GRADE analysis and meta-analysis
Medicine (Baltimore) . 2020 Oct 30;99(44):e22999Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ten randomized controlled trials with a total of 1080 patients undergoing a total hip arthroplasty (THA) or total knee arthroplasty (TKA) were included in this meta-analysis comparing oral tranexamic acid (TXA) or intravenous (IV) TXA. The primary outcomes of interest included Hemoglobin (Hb) drop, total blood loss, and transfusion rate. Secondary outcomes of interest included drain blood loss, le...
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