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Oral pregabalin ineffective for pain reduction after posterior spinal fusion surgery in adolescents
March 2020
Oral pregabalin ineffective for pain reduction after posterior spinal fusion surgery in adolescents
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Preemptive Pregabalin in Children and Adolescents Undergoing Posterior Instrumented Spinal Fusion: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial.
J Bone Joint Surg Am. 2020 Feb 5;102(3):205-212.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Sixty-four adolescent patients scheduled for a posterior spinal fusion surgery were randomized to receive peri-operative oral pregabalin or placebo for the reduction of pain and opioid consumption post-operation. The primary outcomes of interest were oxycodone cumulative consumption and oxycodone consumption rate. Secondary outcomes of interest included pain scores on the Scoliosis Research Societ...
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