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ACE Report #11134
Ace Report Cover Sports Medicine

Postoperative blood loss reduced with IV TXA in single-bundle ACL reconstruction

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:1

Single Intravenous Administration of Tranexamic Acid in Anterior Cruciate Ligament Reconstruction to Reduce Postoperative Hemarthrosis and Increase Functional Outcomes in the Early Phase of Postoperative Rehabilitation: A Randomized Controlled Trial

Arthroscopy. 2019 Jan;35(1):149-157. doi: 10.1016/j.arthro.2018.07.050

Contributing Authors: M Formica L Felli S Revello G Burastero P Gatto A Carletti M Alessio-Mazzola

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80 patients scheduled for single-bundle anterior cruciate ligament reconstruction were randomized to intravenous administration of either 15mg/kg tranexamic acid or placebo saline. The study was conducted to determine if there was a significant difference between groups in 24-hour drainage volume. In addition, hemarthrosis grading, limb circumference, pain, quadriceps strength, functional scores, ...

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