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No difference observed over 1 year between high and low molecular weight HA for knee OA treatment
May 2019
No difference observed over 1 year between high and low molecular weight HA for knee OA treatment
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Comparison of two different molecular weight intra-articular injections of hyaluronic acid for the treatment of knee osteoarthritis
Hippokratia. 2016 Jan-Mar;20(1):26-31Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
80 patients with Kellgren-Lawrence grade II-IV knee osteoarthritis were randomized to a course of five weekly intraarticular injections of either low molecular weight hyaluronic acid or high molecular weight hyaluronic acid. Patients were assessed for response the therapy in a visual analog scale for pain, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and medial and l...
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