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Assessment of IV, IA, and oral tranaexamic acid safety in total joint arthroplasty
November 2018
Assessment of IV, IA, and oral tranaexamic acid safety in total joint arthroplasty
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
The Efficacy of Tranexamic Acid in Total Hip Arthroplasty: A Network Meta-analysis
J Arthroplasty. 2018 Oct;33(10):3083-3089.e4. doi: 10.1016/j.arth.2018.06.023Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
78 randomized controlled trials were included in this meta-analysis, which sought to evaluate the incidence of venous and arterial thromboembolic (VTE and ATE) events associated either intravenous, intraarticular, and oral tranexamic acid, and compare rates to placebo or control intervention groups. No analysis demonstrated a significant increase in the risk of VTE or ATE complications with either...
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