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Noninferior improvement in function over 24 weeks with Structovial HA vs Hylan G-F 20 HA for knee OA
April 2019
Noninferior improvement in function over 24 weeks with Structovial HA vs Hylan G-F 20 HA for knee OA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Comparative efficacy and safety of two different molecular weight (MW) hyaluronans F60027 and Hylan G-F20 in symptomatic osteoarthritis of the knee (KOA). Results of a non inferiority, prospective, randomized, controlled trial.
Clin Exp Rheumatol. 2011 May-Jun;29(3):527-35Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
279 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to three weekly intraarticular injections of either F60027 sodium hyaluronate (Structovial; Pierre Fabre) or Hylan G-F20 (Synvisc). The primary purpose of this study was to examine if F60027 was noninferior to Hylan G-F20 for functional improvement over 24-week follow-up. Mean improvement in Lequesne Index score f...
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