Bisphosphonates in revision THA ineffective in altering pseudomembrane cytokine expression
Effect of alendronate on pseudomembrane cytokine expression in patients with aseptic osteolysisJ Arthroplasty. 2010 Sep;25(6):958-63
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10 patients, scheduled for revision hip arthroplasty due to aseptic osteolysis, were randomized into two groups, one received the alendronate for 8 weeks prior to surgery and another received placebo. The pseudo membrane was harvested at the time of surgery and immunohistochemistry and various cytokine expressions were tested in the two groups. In conclusion, the alendronate therapy prior to revis...
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