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RCT
ACE Report #10381
Ace Report Cover Cannabis

Oral dronabinol and smoked cannabis have similar psychoactive effects, but peak at different times


Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

The subjective psychoactive effects of oral dronabinol studied in a randomized, controlled crossover clinical trial for pain

Clin J Pain. 2014 Jun;30(6):472-8. doi: 10.1097/AJP.0000000000000022

Contributing Authors: S Narang AD Wasan E Michna RN Jamison MA Issa RR Edwards DM Penetar

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Synopsis

30 patients with chronic pain took placebo, 10 mg or 20 mg oral dronabinol at 3 sessions in a randomly allocated sequence. They were compared to 20 patients without chronic pain who smoked a 1.99% and 3.51% THC marijuana cigarette at each session. Both groups were given the Addiction Research Center Inventory to determine whether oral dronabinol and smoked cannabis have similar psychoactive effect...

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