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Nabilone reduces pain and improves sleep and quality of life in diabetic peripheral neuropathic pain
October 2018
Nabilone reduces pain and improves sleep and quality of life in diabetic peripheral neuropathic pain
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo-controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain
Pain. 2012 Oct;153(10):2073-82. https://dx.doi.org/10.1016/j.pain.2012.06.024Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
26 adults with diabetic neuropathic pain were randomized to receive either oral nabilone (a synthetic cannabinoid) or placebo for 5 weeks. The primary outcome was the average daily pain score, and secondary outcomes included sleep, anxiety, depression, treatment satisfaction, and quality of life. Results demonstrated that nabilone was more effective than placebo for reducing pain, improving sleep...
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