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Volume:7 Issue:2 Number:11 ISSN#:2563-5476
RCT
ACE Report #10084
Ace Report Cover Osteoarthritis

Assessing efficacy of an autologous protein solution injection versus saline for knee osteoarthritis


How to Cite

OrthoEvidence. Assessing efficacy of an autologous protein solution injection versus saline for knee osteoarthritis. ACE Report. 2018;7(2):11. Available from: https://myorthoevidence.com/AceReport/Report/10084

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:2

Clinical Outcomes of Knee Osteoarthritis Treated With an Autologous Protein Solution Injection: A 1-Year Pilot Double-Blinded Randomized Controlled Trial

Am J Sports Med. 2018 Jan;46(1):171-180.

Contributing Authors: L Engebretsen R Verdonk E Kon G Filardo S Nehrer

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Synopsis

46 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized in a 2:1 fashion to intraarticular injection of either the Autologous Protein Solution blood product (nSTRIDE APS; Biomet Zimmer) or placebo saline. Patients were assessed for clinical measures and imaging results over a 12-month follow-up. For pain, the WOMAC pain score demonstrated favourable improvement in the A...

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