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Efficacy of acetaminophen - with and without tramadol - for analgesia in extremity fracture fixation

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Ace Report Cover
February 2018

Efficacy of acetaminophen - with and without tramadol - for analgesia in extremity fracture fixation

Vol: 7| Issue: 2| Number:3| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:1

Pain Relief After Operative Treatment of an Extremity Fracture: A Noninferiority Randomized Controlled Trial

J Bone Joint Surg Am. 2017 Nov 15;99(22):1908-1915

Contributing Authors:
D Ring GTT Helmerhorst R Zwiers P Kloen

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Synopsis

52 patients with an extremity fracture and scheduled for fixation were randomized to postoperative analgesia with acetaminophen with or without tramadol. The purpose of this study was to determine if acetaminophen alone provided noninferior analgesia to the combination of acetaminophen and tramadol. At 2 week follow-up, noninferiority was observed in assessments of current pain and satisfaction, t...

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