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OTS povidone-iodine vs. PI-based skin and nasal antiseptic vs. placebo in orthopaedic surgery
February 2018
OTS povidone-iodine vs. PI-based skin and nasal antiseptic vs. placebo in orthopaedic surgery
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Povidone-Iodine-Based Solutions for Decolonization of Nasal Staphylococcus aureus: A Randomized, Prospective, Placebo-Controlled Study
J Arthroplasty. 2017 Sep;32(9):2815-2819Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
429 patients scheduled for major orthopaedic surgery were randomized to nasal decolonization with either an off-the-shelf povidone-iodine solution, a specialized Skin and Nasal Antiseptic povidone-iodine solution (3M), or placebo saline swabs. Patients were assessed for Staphylococcus aureus (S. aureus) colonization of the nares. Nasal S. aureus colonization rate was assessed at 4 hours and 24 hou...
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