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E. coli-derived rhBMP-2 offers similar fusion success to AIBG in posterolateral lumbar fusion
January 2018
E. coli-derived rhBMP-2 offers similar fusion success to AIBG in posterolateral lumbar fusion
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Efficacy of Escherichia coli-derived recombinant human bone morphogenetic protein-2 in posterolateral lumbar fusion: an open, active-controlled, randomized, multicenter trial
Spine J. 2017 Dec;17(12):1866-1874Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
100 patients scheduled for posterolateral fusion due to severe spinal stenosis, grade 1 spondylolisthesis, or spondylolysis were randomized to graft material of either Escherichia coli-derived recombinant human bone morphogenetic protein-2 (rhBMP-2) in a hydroxyapatite carrier or an autologous iliac crest bone graft. Patients were assessed primarily for fusion success on CT at 12 and 24 weeks. Sec...
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