OrthoEvidence identified published meta-analyses that assessed the use of intra-articular hyaluronic acid and platelet-rich plasma in the treatment
of osteoarthritis through a search of electronic databases, reviewing the reference list of included publications,
and suggestions from experts in the field.
The inclusion criteria for meta-analyses were: 1) inclusion of only randomized controlled trials,
2) provided a comparison of intra-articular hyaluronic acid to platelet-rich plasma, and 3) evaluated pain, function, or stiffness outcomes.
Data from each of the included meta-analysis was extracted and summarized in the tables below below regarding effect size, statistical significance, and results by patient & product characteristics.
Additional information for each included meta-analysis can be found in the corresponding ACE Report, which can be accessed by
clicking on the trial ID within the table. To learn more about the ACE report creation process, click here