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No significant difference in the incidence of VTE between IV TXA and control in orthopaedic surgery
February 2019
No significant difference in the incidence of VTE between IV TXA and control in orthopaedic surgery
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
Safety of intravenous tranexamic acid in patients undergoing major orthopaedic surgery: a meta-analysis of randomised controlled trials
Blood Transfus. 2018 Jan;16(1):36-43Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
73 randomized controlled trials were included in this meta-analysis investigating the incidence of venous thromboembolic complications between patients administered intravenous tranexamic acid and patients who were not administered TXA. Meta-analysis demonstrated no significant difference between IV TXA groups and control groups in the incidence of VTE complications, which were estimated at 2.1% a...
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